Sioux Falls, South Dakota

Medical Weight Loss Clinics in Sioux Falls

Quick answer

There are 17 weight loss clinics listed in the Sioux Falls area. The highest-rated of them is Refined Aesthetics (5★ from 760 Google reviews). Among the clinics listed here that publish a price, monthly programs run $10–$1,500/month (1385 of the 14845 clinics listed). Telehealth options are available for patients who prefer online care.

Tap a pin on the map to open that clinic's profile, or compare the full listings below it.

Area map

Ordered by Google rating, then by how many reviews it is based on. A rating built on fewer than 5 reviews doesn't rank, so 2 clinics sit lower than their star scores alone would suggest — five stars from a single review isn't better than three stars from fourteen. The 2 clinics we don't have a rating for yet are listed alphabetically after.

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Refined Aesthetics Verified listing
4610 S Technopolis Dr, Suites 31, 35, & 37, Sioux Falls, SD, 57106
5(760)
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Vital Flow Infusions Verified listing
119 S Main Ave, Sioux Falls, SD, 57104

$199–599/mo

5(308)
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Novo Aesthetics Verified listing
4900 E 57th St Ste B, Sioux Falls, SD, 57108·Telehealth
5(236)
CRNA
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Liv Med Spa Verified listing
3800 E Vendavel St, Sioux Falls, SD, 57108·Telehealth
5(198)
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4908 E Rosa Parks Pl, Sioux Falls, SD, 57110
5(178)
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The Confidence Collective Verified listing
5124 S Western Ave, Suite 4, Sioux Falls, SD, 57108
5(157)
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iv&co. Verified listing
345 N. Reid Pl., Suite 123, Sioux Falls, SD, 57103
5(64)
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Era Health & Hormone Verified listing
5617 S Southeastern Ave, Sioux Falls, SD, 57108
5(43)
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Thrive & Co. Verified listing
7520 South Grand Arbor Court Suite 135, Sioux Falls, SD, 57108·Telehealth

$215/mo

med. included

5(19)
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We Build Champions Verified listing
5009 S Bur Oak Place, Sioux Falls, SD, 57108
5(6)
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ONE80 Verified listing
6300 S Old Village Pl Unit 203, Sioux Falls, SD, 57108
4.9(487)
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4301 W 57th St #160, Sioux Falls, SD, 57108·Telehealth
4.9(421)
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Limitless Male Verified listing
5919 S Remington Pl Ste 200, Sioux Falls, SD, 57108
4.6(117)
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3401 W 49th St, Sioux Falls, SD, 57106
5(1)
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Functional Health Clinic Verified listing
2101 West 41st Street, Suite 113, Sioux Falls, SD, 57105·Telehealth
4(4)
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4301 W 57 th St, Suite 160, Sioux Falls, SD, 57108·Telehealth
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Peakform Wellness Clinic Verified listing
2333 W 57th St Ste 102, Sioux Falls, SD, 57108·Telehealth

More weight loss options near Sioux Falls

1 more clinic in one nearby town within 25 miles of Sioux Falls. A short drive can mean more choice, better pricing, or an earlier appointment.

Frequently Asked Questions — Medical Weight Loss in Sioux Falls

How much does Weight Loss cost in Sioux Falls?

Among the clinics listed here that publish a price, monthly medical weight loss programs run $10–$1,500/month (1385 of the 14845 clinics listed). Most clinics publish no price at all. Use our free cost calculator for a personalized estimate.

Are there board-certified doctors for Weight Loss in Sioux Falls?

Many clinics in Sioux Falls are physician-led, and the credential pills on each listing show what the clinic itself publishes about its providers — hover any pill for a plain-English explanation. We do not independently verify board certification today, so if it matters to you, verify the specific physician on the free NPPES registry and the relevant specialty board before booking.

Can I get Weight Loss treatment online in South Dakota?

Telehealth options are available in most states including South Dakota. Online providers typically offer lower prices and home delivery of medications. Filter by "Telehealth available" to see online options.

How do I know if a clinic is legitimate?

Look for the "Verified listing" badge — it means we confirmed this is a real, operating business at a real address, with services matching what the clinic itself publishes. It is not a review of the providers' credentials. Before booking, it is worth checking the physician's NPI number on the free NPPES registry and their state medical license status yourself.

Telehealth options in Sioux Falls, SD

Online care, no travel

These online providers offer medical weight loss care to patients in Sioux Falls and across South Dakota — licensed clinicians, home delivery, no office visit required.

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RoOnline provider

Chat-based GLP-1 care, no video visit required

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Hims & HersOnline provider

Most versatile telehealth platform

Weight LossHormones★ Trustpilot reviews
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Mochi HealthOnline provider

Publishes a separate price for every medication it offers

🔴
Henry MedsOnline provider

Compounded GLP-1 in oral drops, injectable, and tablet formats

🍯
Hone HealthOnline provider

Built around first-time TRT patients

Weight LossHormones★ Trustpilot reviews
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MaximusOnline provider

Performance medicine for men

Weight LossHormonesPeptides★ Trustpilot reviews
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FoundOnline provider

Personalized weight loss with GLP-1 + behavior coaching

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JRNYSOnline provider

GLP-1 weight loss + hormone optimization telehealth

Weight LossHormones★ Trustpilot reviews
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Yucca HealthOnline provider

Multi-service cash-pay telehealth for weight loss & hormones

Weight LossHormonesPeptides★ Trustpilot reviews
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FridaysOnline provider

GLP-1 and hormone health telehealth with transparent pricing

Weight LossHormones★ Trustpilot reviews

* This site may earn a referral fee from online providers. This does not affect our rankings or your cost.