How Much Does Tirzepatide Cost Without Insurance? $299 a Month at 78 Clinics

The short answer

If you pay for tirzepatide yourself at a local clinic, plan on about $299 a month. That is the middle figure among the clinics in this directory that price tirzepatide on its own, and it is also what Eli Lilly charges self-pay patients for the starting dose of Zepbound. A quarter of those clinics start at $172 or less; a quarter start at $397 or more.

Tirzepatide costs more than semaglutide almost everywhere it is sold: at the 50 clinics that publish a price for each, the gap is typically about $100 a month (half are between $94 and $168).

These are the clinics' own published prices, read from the directory on October 30, 2026. We counted a clinic only when its own price words name tirzepatide, and each practice once: 78 clinics. Every one is listed with its source page and the date we read it on semaglutide and tirzepatide prices by state.

Why you will see two different numbers

Most clinics that sell tirzepatide also sell semaglutide, and 61 of the 78 price them on one line: "semaglutide from $125, tirzepatide from $265." So the lowest figure on a clinic's page is usually the semaglutide price. Across all 78 clinics that lowest program price has a median of $230 a month. It is not the tirzepatide price.

Two ways to get the real figure, both from the clinics' own words: the 17 clinics that price tirzepatide alone start at a median of $299 a month, and of the clinics that price both drugs, 50 publish a range whose top is nearly always the tirzepatide price, median $377. So expect $300 to $380 a month, with the first month sometimes cheaper.

The lowest tirzepatide figure in the directory is $90 a month, in Kalispell, Montana. At the other end, two clinics start at $500 or more, one in Dublin, California charges $700 the first month and $800 after, and the highest published figure is $1,200 a month.

Compounded tirzepatide or brand-name Zepbound?

Compounded tirzepatide at a clinic. A compounding pharmacy makes it to the clinic's prescription, usually a vial you inject weekly; it is what most cash-pay clinics sell. The ten clinics that say "compounded" in their price start at a median of about $275 a month.

Brand-name Zepbound or Mounjaro through a clinic. Four clinics name Zepbound or Mounjaro in their price: $379 a month at two sister clinics in California, $389 for a one-month supply in Connecticut, $499.99 in Florida.

Brand-name Zepbound straight from the maker. Eli Lilly sells Zepbound to self-pay patients through LillyDirect, as a vial or a KwikPen. Each figure is kept with its source and date on the Zepbound price page; as of our read on October 28, 2026:

• 2.5 mg (the starting dose): $299 a month.
• 5 mg: $399 a month.
• 7.5 mg and up: $449 a month when you refill within 45 days; $499 (7.5 mg) or $699 (10 mg and up) otherwise.

Savings limits apply and Lilly can change the terms. Mounjaro is the same medicine approved for type 2 diabetes, with no self-pay program and a list price of about $1,080 per fill, which is why people paying cash for weight loss buy Zepbound instead (Mounjaro price page).

If a clinic quotes $400 or more for compounded tirzepatide, ask why the brand-name vial would not cost the same or less.

Does the price include the medicine?

Twenty-six of the 78 clinics say plainly that the medication is in their monthly price. Among those, half start at $250 a month or less, a quarter at $176 or less, and a quarter at $389 or more. Again, the low end is often the semaglutide option.

None of the 78 says outright that the medicine is extra, which only means the page does not say. One Massachusetts practice spells it out: the visit is one fee, and a 4-week supply is "an additional cost of $165 for most doses," rising to $365 for tirzepatide doses over 4 mg. A "program from $199" that never mentions the medicine is usually a price for visits. So ask every clinic the same sentence: *does that include the tirzepatide, every month, at every dose?*

The dose goes up, and so does the bill

Tirzepatide starts at 2.5 mg and is raised over several months, often to 10 or 15 mg, and many clinics price each step. In their own words:

• Corpus Christi, Texas: 2.5 mg $149 a month, 5 mg $199, 7.5 mg $229, 10 mg $249, 12.5 mg $279, 15 mg $299.
• Hialeah, Florida: "starts at $199/month for 2.5mg tirzepatide, with tiers up to $449/month at 15mg."
• Frisco, Texas: $325 the first month, $425 each month after, with a two-month commitment.

Fifty-six of the 78 clinics publish a range rather than one figure, and the median top of those ranges is $370 a month. The starting price is month one. If a clinic shows you only that, ask what month four costs.

The first visit

Most clinics charge for the first appointment: a history, usually bloodwork, and the prescription. Across all weight loss clinics publishing a first-visit fee the median is $140, and 213 say it is free. Among these 78 tirzepatide clinics, 25 publish a fee, median $105. A cheap first visit means the clinic earns on the monthly program, so make sure that price is on the website. What a first visit costs lists every published fee by state.

By state

Only two states have ten or more clinics publishing a tirzepatide price, so this table is short on purpose. The figure is the lowest published program price, usually the semaglutide option; add about $100 for tirzepatide.

Texas (7 clinics), Massachusetts (6) and Arizona (5) come next. Everywhere else the count is too small to call typical, so look at your own state's list; within one state the cheapest and dearest clinic are often $400 apart.

Online, local, or the maker?

The online providers listed on this site charge $99 to $548 a month across their programs, in line with the median local clinic. A local clinic gives you a person in the room: bloodwork, an exam, someone to call when a side effect turns up. If your medical history is simple, the maker's $299 vial is the easiest place to start comparing. Online vs. local GLP-1 provider walks through the trade-off.

Insurance sometimes covers Zepbound after prior authorization; it almost never covers compounded tirzepatide, and the maker's self-pay price does not count toward your deductible.

Five questions to ask before you pay

1. Is this compounded tirzepatide or brand-name Zepbound, and what does each cost here?
2. Does the monthly price include the tirzepatide, at every dose, every month?
3. What does the price become at 10, 12.5 and 15 mg?
4. Are the first visit and the bloodwork in the price or extra?
5. Can I stop month to month, or am I signing up for a term?

A clinic that answers all five on its website is one you can compare.

The bottom line

Without insurance, budget about $299 a month for tirzepatide at a local clinic, and expect it to climb toward $370 or more as the dose goes up. Check the maker first: Zepbound is $299 a month at 2.5 mg, $399 at 5 mg and $449 from 7.5 mg up when you refill on time. The cheapest clinics beat that; the most expensive charge $500 to $800 and should be able to say what that buys.

Weighing the two drugs? Tirzepatide vs. semaglutide covers the difference, and what semaglutide costs without insurance gives the same figures for the cheaper one.

See every clinic's published tirzepatide price in your state →