Clinic 45

About Clinic 45

What is Clinic 45?

Clinic 45 is a weight loss and aesthetic center at 8221 Gulf Fwy Ste 400, Houston, TX 77017, phone (713) 999-5161. It calls itself an independent medical spa and practice. Weight loss is listed first, and aesthetic treatments make up much of the rest.

Joseph E. Sleiman M.D. owns and supervises the practice and is the only prescriber it names. The weight loss program says patients are seen monthly by licensed medical providers, but it does not name them.

Services include weight loss injections and supplements, Testosterone Replacement Therapy (TRT), IV therapy, Botox and dermal fillers, microneedling, laser hair removal and skin tightening. It names Semaglutide, Tirzepatide, NAD+ and phentermine. It does not describe peptide or anti-aging programs. Telehealth is offered for weight loss consultations and check-ups. The clinic claims 20 years of experience and 6 locations across Texas, but it shows only the Houston address. It has a 4.8 rating on Google from 1368 reviews.

What does it cost?

Clinic 45 does not publish prices. It does not state a consultation fee, whether medication is part of a monthly fee, whether it accepts insurance, or whether it offers financing. Get a written quote covering the first visit, medication, lab work and each monthly follow-up before you pay.

What should you ask before you book?

Ask who writes the prescription. The clinic names Joseph E. Sleiman M.D., but the monthly visits are with licensed providers it does not name, so ask whether you would see him, someone else, or both.

In its own words: "we can prescribe weight loss medication, including appetite suppressant pills such as phentermine pills, or recommend semaglutide injections as part of your medical weight loss program." Ask which of those applies to you and what each one requires.

Ask whether the monthly fee includes medication, and whether the drugs are brand-name or compounded. The clinic mentions "In-House Semaglutide injections," so ask where that medication is made. Ask what the first visit costs, including blood tests, body composition analysis and any EKG, plus the cost of each follow-up and how cancellation works. Ask whether bariatric surgery is done in this office or referred out, since the program page mentions it.

Who is it a good fit for?

This is a good fit if you want medical weight loss in Houston, possibly alongside aesthetic work in the same office, and you are willing to get every cost in writing before you commit. It is a weaker fit if you need published prices or a clear answer on insurance before you call.

Sources: clinic45.com, clinic45.com/weight-loss

Services Offered

Location