Upgrade Medical
Verified listingAbout Upgrade Medical
What is Upgrade Medical?
Upgrade Medical is a clinic at 1210 NW Johnson St., Portland, OR 97209. Its phone number is (971) 299-8350. It describes itself as focused on antiaging, longevity, optimization, and human performance, and hormones and peptides take up much of what it offers. Its services are Functional and Metabolic Medicine, Hormones and Peptides, Anti-aging and Longevity, Regenerative and Restorative Medicine, and Performance Optimization. It is open Monday, Wednesday, and Thursday, with Friday and Saturday hours on alternating weeks, and closed Tuesday and Sunday.
Chris A. Kleronomos is the prescriber, known as Dr. K. No degree or license appears after his name, so none is given here. Upgrade Medical says he has two decades of clinical experience and has served as a medical director, national lecturer, educator, and founder of multiple integrative and functional medicine programs. Consultations begin with screenings and measures reviewed before your visit, followed by a one-on-one visit of 75 to 90 minutes with Dr. K.
Semaglutide and tirzepatide appear among its metabolic peptides, and sermorelin and tesamorelin among its growth hormone peptides. Its Google listing shows a rating of 5 from 80 reviews.
What does it cost?
Upgrade Medical does not publish prices, a consultation fee, or membership terms. Memberships appear among its menu items, but no terms come with them. Its only payment line reads "HSA Eligible Services Available*". It does not say whether it accepts insurance, or whether medication is included in any program fee. Plan on paying the full cost yourself until it confirms in writing what HSA funds can cover.
What should you ask before you book?
Ask who signs the prescription, and whether Dr. K writes it personally. Ask whether a monthly fee or program price includes the medication, and what the medication costs on its own. Ask whether semaglutide and tirzepatide are brand-name or compounded. In its own words: "Not all peptides are FDA approved." That makes a good opening to ask which products it uses and where they come from.
Ask what follow-up visits and lab work cost, and whether the at-home lab draws through its partners Siphox, Genova, DUTCH, and Vibrant are billed separately. Ask how to cancel a membership or program, and whether a cancellation fee applies. Ask whether telehealth is offered, since the clinic's offering on that point is not stated. Ask which weeks carry the alternating Friday and Saturday hours.
Who is it a good fit for?
This is a good fit if you want in-person care in Portland, expect to pay the full cost yourself or with HSA funds, and will get prices and cancellation terms in writing before you book. It is a weaker fit if you need a firm price before your first visit or want video visits, since neither is stated.
Sources: upgradepdx.com, upgradepdx.com/peptides-and-hormone-therapy, upgradepdx.com/legacy-hormones-and-peptides, upgradepdx.com/anti-aging-longevity, upgradepdx.com/meet-dr-k
Services Offered
What we confirmed
Read off Upgrade Medical’s own website on 2026-10-11. These are their words, not ours.
- ✓Medical weight loss — listed on their site as “Semaglutide” source
- ✓Hormone therapy — listed on their site as “We move beyond basic symptom management to strategically optimize your entire endocrine matrix using bioidentical hormones tailored to your exact data.” source
- ✓Peptide therapy — listed on their site as “Peptides are chains of amino acids that act as cell signaling molecules that bind to the cell surface receptors, triggering an intracellular action.” source
- ✓Longevity / anti-aging — listed on their site as “At Upgrade Medical, longevity is a deliberate clinical strategy.” source