ManUP Testosterone Center

Verified listing
8635 Mexico Rd., O'Fallon, MO, 63366
4.4(47 Google reviews)
Read reviews on Google ↗as of Oct 2026

About ManUP Testosterone Center

What is ManUP Testosterone Center?

ManUP Testosterone Center is a cash-pay practice with five locations in O'Fallon, St. Peters, Ellisville, Fenton and Washington, Missouri. Its main work is hormone therapy, including men's testosterone replacement (TRT) and women's hormone replacement (HRT), with the women's side also branded WomanUP. Medical weight loss is one of its services, alongside IV therapy, EMS Body Sculpt, EMS Kegal Chair and laser hair removal. It has been seeing patients across the St. Louis region for over a decade. Google lists it as a medical clinic, with a 4.9 rating from 23 reviews.

Its licensed providers use GLP-1 medications and older weight loss medications, sometimes in combination. The named medications are semaglutide (Ozempic/Wegovy), tirzepatide (Mounjaro/Zepbound), Saxenda (liraglutide), phentermine, phendimetrazine, metformin and naltrexone. It also names retatrutide, which it labels investigational. Peptide therapy appears in its own description: "Our clinic specializes exclusively in hormone optimization, medically assisted weight loss, and peptide therapy treatments."

This listing is for its O'Fallon office at 8635 Mexico Rd..

What does it cost?

It does not publish prices. It gives no consultation fee and no cancellation or commitment terms. Its weight loss programs are described as monthly protocols that include medication and medical supervision, but no dollar figure appears, and it is not clear whether that holds for combination plans. Payment options include cash, check, credit and debit cards, healthcare financing, monthly payment plans and package deals. It does not work through insurance. In its own words: "Your primary care can only do so much within the guidelines of insurance, because we don’t work through insurance, we can create the most affordable way for you to notice and maintain results."

What should you ask before you book?

Ask who writes the prescription, since no prescriber is named. Ask whether the monthly fee includes the medication, and whether each drug is brand-name or compounded. Ask what the consultation costs, and what the initial labs, follow-up visits and routine testosterone blood checks cost. Ask whether those are part of the program price. Ask how cancellation works and whether there is a minimum commitment. Ask whether follow-up visits can be done by video, since telehealth is not mentioned. If peptide therapy interests you, ask what it involves and what it costs, because it is not on the service list. If a plan includes retatrutide, ask what "investigational" means for your treatment and how the clinic handles it.

Who is it a good fit for?

This is a good fit if you plan to pay out of pocket for hormone therapy or medical weight loss and are willing to get the prescriber, price and cancellation answers in writing before you commit. If you need a named prescriber, a published price or a stated cancellation policy before you call, hold off until you have them.

Sources: manup-womanup.com, manup-womanup.com/medical-weight-loss, manup-womanup.com/hormone_weight_loss-clinic-st-peters, manup-womanup.com/glp1-medications

Services Offered

✓Men’s TRT
✓Women’s HRT
✓IV Therapy
✓EMS Body Sculpt
✓EMS Kegal Chair
✓Laser Hair Removal

What we confirmed

Read off ManUP Testosterone Center’s own website on 2026-10-11. These are their words, not ours.

  • ✓Medical weight loss — listed on their site as “Semaglutide (Ozempic/Wegovy)” source
  • ✓Hormone therapy — listed on their site as “Hormone Replacement Therapy for Men” source
  • ✓Peptide therapy — listed on their site as “our clinic specializes exclusively in hormone optimization, medically assisted weight loss, and peptide therapy treatments” source

We have not yet collected published prices or prescriber credentials for this clinic. When we do, they will appear here with a link to the page they came from — or a note saying the clinic publishes none, which is itself worth knowing. Call them for a price in the meantime.

Hours

Monday,Wednesday 09:00-18:00; Tuesday,Thursday 09:00-17:00; Friday 09:00-17:30