XO Aesthetic Refinery

Verified listing
3744 Frankfort Avenue (St. Matthews, Louisville, KY, 40207
5.0(425 Google reviews)
Read reviews on Google ↗as of Oct 2026
CRNA

About XO Aesthetic Refinery

What is XO Aesthetic Refinery?

XO Aesthetic Refinery is a med spa in Louisville, KY. Most of its listed services are aesthetic: neurotoxins (Botox, Dysport, Daxxify, Xeomin and Jeuveau), dermal and lip fillers, Sculptra and Radiesse biostimulators, facials, chemical peels, microneedling, permanent makeup and spray tans. Google lists it as a medical spa, with a 5 rating from 425 reviews.

Medical weight loss with GLP-1 medications is one of its listed services. It sits under a Medical & Wellness heading, along with NAD+ and IV drip hydration.

Its team list gives five clinicians with credentials. Jana Brewer, CRNA, is listed as medical director. Hannah Stearns, APRN; Lauryn Lee, RN; Jessca Orangias, NP; and Kasi Suarez-Poulton, RN, are listed as injectors. The team list does not say which of them handles the weight loss or NAD+ care.

What does it cost?

The clinic does not publish prices, including for the GLP-1 and NAD+ services. Its services page says: "For all pricing, visit our 'Book Now' tab." It does not publish a consultation fee, and it does not say whether medication is included in any program.

It says it offers multiple payment options, and its payment page points to a Cherry estimator for working out what a monthly payment could be. It does not say whether insurance is accepted.

What should you ask before you book?

Ask who prescribes GLP-1 and NAD+ care and what credential that person holds, since the clinic does not name a prescriber for either service. Ask whether a monthly program price includes the medication, and whether that medication is brand-name or compounded. Ask what follow-up visits and lab work cost, and how a program is cancelled or paused.

Ask whether telehealth is offered and what the office hours are, since neither is listed. No street address or ZIP code is published, and the phone number, 323-929-5874, carries a 323 area code, not a Louisville one. Ask for the street address before you go. If hormone therapy or peptide therapy is what you came for, ask about it directly, because neither is among its listed services.

Who is it a good fit for?

This is a good fit if you want injectables, skin treatments or the listed weight loss program from a med spa, and you are comfortable confirming who prescribes, what a monthly price covers and what you will pay in total before you agree to anything. It is a weaker fit if you need hormone therapy or want prices you can see before you call.

Sources: xoaestheticrefinery.com, xoaestheticrefinery.com/services-3, xoaestheticrefinery.com/team-3, xoaestheticrefinery.com/payment-plans

Services Offered

✓Neurotoxins (Botox, Dysport, Daxxify, Xeomin, Jeuveau)
✓Refinery Custom Facial
✓Hydrafacial
✓Chemical Peels
✓Acne Bootcamp
✓FaceTite & BodyTite
✓Dermal Filler
✓Lip Filler
✓Biostimulators (Sculptra, Radiesse)
✓PRP / PRF Injections
✓Microneedling
✓RF Microneedling (Morpheus8 / CO2)
✓PDGF (Growth Factor Therapy)
✓Permanent Makeup (Brows, Lip Blushing, Freckles)
✓Spray Tan
✓Medical Weight Loss: GLP1s
✓NAD+
✓IV Drip Hydration
✓Dermaplane
✓Facial Waxing (Lip, Brow)

What we confirmed

Read off XO Aesthetic Refinery’s own website on 2026-10-13. These are their words, not ours.

  • ✓Medical weight loss — listed on their site as “Medical Weight Loss: GLP1s” source
  • ✓Longevity / anti-aging — listed on their site as “NAD+” source