Performance Medical Clinic

Verified listing
1181 State Route 157, Suite 1B, Edwardsville, IL, 62025
5.0(534 Google reviews)
Read reviews on Google ↗as of Oct 2026

About Performance Medical Clinic

What is Performance Medical Clinic?

Performance Medical Clinic is a medical practice at 1181 State Route 157, Suite 1B, Edwardsville, IL 62025. Its main work is hormone and longevity medicine, with medical weight loss as one of several programs. Dr. Michael Ambrose, DC, MD, is the physician named as prescriber. The clinic describes him as a board-certified internal medicine physician who also trained as a chiropractor, with added training in anti-aging medicine and hormone replacement therapy.

The clinic also lists low testosterone, erectile dysfunction, thyroid, LDN therapy, and platelet rich plasma and stem cell treatments. Its weight loss program may include a history and physical, lab work when indicated, body composition testing, compounded semaglutide or tirzepatide injections, other medications or peptides, diet and lifestyle guidance, and regular follow-up visits. Hormone therapy is offered as pellets, creams or injections. Hours are 8:00am to 6:00pm Monday through Thursday, with Friday visits by appointment. It has a 5 star rating on Google from 534 reviews. Phone: (618) 671-6800.

What does it cost?

It does not publish prices. No consultation fee, medication price, membership fee or financing option is listed. It does not say whether medication is included in any price, whether it accepts insurance, or what lab work and follow-up visits cost. Get each of those figures in writing before you book, along with the cancellation terms.

What should you ask before you book?

Ask who writes the prescription and whether Dr. Ambrose sees you in person before treatment starts. The clinic does not say whether it offers telehealth, so ask directly. Ask whether the monthly fee includes the medication. For the weight loss injections, ask whether the drug is compounded or an FDA-approved brand, and which pharmacy makes it. The clinic's own disclaimer addresses this point. In its own words: "Any Compounded Semaglutide formulations prescribed by this clinic have been compounded by a licensed compounding pharmacy, but any such products have not been evaluated by the US Food and Drug administration (FDA) for safety, effectiveness, or quality."

For hormone therapy, ask which delivery method is recommended and what each one costs, since the methods involve different visits. Ask what follow-up labs and visits cost, whether insurance is accepted, and what a visit costs without it. Ask how to cancel and whether a membership renews automatically. Ask whether weekend times are available, since none are listed.

Who is it a good fit for?

This is a good fit if you want weight loss medication, hormone therapy and longevity testing under one physician, and you are willing to get a written price and a clear answer on the prescription before you commit. If you need a published price list before you call, or you need to know whether insurance applies before you schedule, wait for those answers before you book.

Sources: performancemedicalclinic.com/edwardsville, performancemedicalclinic.com/lowtestosterone, performancemedicalclinic.com/medicalweightloss, performancemedicalclinic.com/bioidenticalhormonetherapy, performancemedicalclinic.com/peptides, performancemedicalclinic.com/longevity

Services Offered

✓Bioidentical Hormone Therapy
✓Low Testosterone
✓Erectile Dysfunction
✓Longevity Medicine
✓Medical Weight Loss
✓Thyroid
✓LDN Therapy
✓Peptide Therapy
✓Platelet Rich Plasma/Stem Cell

What we confirmed

Read off Performance Medical Clinic’s own website on 2026-10-11. These are their words, not ours.

  • ✓Medical weight loss — listed on their site as “Compounded Semaglutide / Tirzepatide Injections:” source
  • ✓Hormone therapy — listed on their site as “Bio-Identical Hormone Replacement Therapy (also known as BHRT)” source
  • ✓Peptide therapy — listed on their site as “PEPTIDE THERAPY” source
  • ✓Longevity / anti-aging — listed on their site as “LONGEVITY MEDICINE AND ANTI-AGING” source

Location