The Center for Transformational Medicine
Verified listingAbout The Center for Transformational Medicine
The Center for Transformational Medicine is a single-physician integrative practice at 2617 East Chapman, Suite #204, Orange, built around hormone therapy rather than weight loss. Menopause, andropause, bioidentical hormone replacement and the Wiley Protocol are the core of it. No price appears anywhere on the site, and no statement says whether insurance is accepted.
## What does the practice treat?
Seven services are listed: integrative internal medicine, menopause, hormone replacement therapy, the Wiley Protocol, andropause, sexual medicine and anti-aging. The hormone page names three medications, estradiol, progesterone and testosterone. The Wiley Protocol is a specific named bioidentical rhythmic-dosing protocol, and offering it by name is a real point of difference from a clinic that simply says "bioidentical hormones". One thing this practice is not: a weight-loss clinic. No weight-loss service, no GLP-1, no semaglutide, no tirzepatide and no peptide therapy appears anywhere on the site.
## How does treatment actually run?
The published rhythm is unusually concrete for a site this small. New patients download patient forms ahead of the appointment. After starting therapy, follow-ups come at one month and three months. After that, the page describes three to four visits per year, generally with lab work at each visit. That gives you a reasonable sense of the ongoing commitment even though the cost of it is not stated.
## What does it cost, and does insurance apply?
Neither question is answered on the site. No price, consultation fee, membership or fee schedule appears on any page in the navigation, and there is no financial-policy page. The site never says it accepts insurance, and it never says it is cash-pay, so neither can be inferred here. For a practice whose treatment pattern involves several visits and labs each year, that is a significant gap, and it is worth settling on the phone before a first appointment.
## Who is the physician, and when is the office open?
One clinician practises here, published as Gregory H. Wolf, M.D, with the name written exactly that way on the site. His credentials are spelled out rather than abbreviated: board certified in Family Medicine, a Diplomate of the American Board of Family Medicine, and a Fellow of the American Academy of Family Practice. The most recent recertification published is 2006. On tenure, the site publishes three separate claims: private practice in Orange since 1985, anti-aging and integrative medicine since 1993, and a 30 year career in bio-identical hormone replacement therapy. Hours follow a distinctive split-day pattern. Monday, Tuesday and Wednesday run 9:00 a.m. to 12:00 p.m. and again 2:00 p.m. to 4:00 p.m. Thursday is closed all day. Friday is 9:00 a.m. to 1:00 p.m.
## What we could not confirm
Any dollar amount at all. Any insurance statement. Any telehealth or virtual-visit offering, and any list of states served. Any service-area statement. Any published eligibility criteria describing who the practice is for. There is also no FAQ page, no terms or financial-policy page, and no second provider or staff member named anywhere. All of this was checked on 22 September 2026.
**Sources:** https://www.gregorywolfmd.com/services/ · https://www.gregorywolfmd.com/hormone-replacement-therapy/ · https://www.gregorywolfmd.com/about-dr-wolf/ · https://www.gregorywolfmd.com/new-patients/ · https://www.gregorywolfmd.com/contact/