The VitalityMatch Library

Guides & Comparisons

Honest, research-backed guides on GLP-1, TRT, peptides, and longevity medicine. We compare providers, explain costs, and help you make an informed decision — without the sales pitch.

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Medical Weight Loss

6 min

Online vs. Local GLP-1 Provider: Which Is Right for You?

There are three ways to get a GLP-1 now, not two — telehealth from $99/mo, the manufacturer direct from $149, or a local clinic. What each one actually buys you, and how to pick.

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6 min

How to Choose a GLP-1 Clinic: What to Ask Before You Sign Up

Six questions that separate credible medical weight loss clinics from thin med-spas — and what the answers should tell you.

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9 min

What Does GLP-1 Actually Cost? A Complete Price Guide

Real published GLP-1 prices: $299–$449/mo for Zepbound and $349/mo for Wegovy direct from the manufacturers, $99–$548/mo through telehealth, and $50 for eligible Medicare patients. Every figure below traces to a published source.

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10 min

Best Weight Loss Telehealth Platforms: Ranked & Compared

We compared Ro, Hims/Hers, Mochi Health, Henry Meds, and more on price, medication options, and patient experience. Here's who wins — and for whom.

8 min

Weight Loss Medications Explained: GLP-1s, How They Work, and What to Expect

How GLP-1s like Ozempic, Zepbound and the new oral options actually work, honest side effects, who qualifies, and what a realistic treatment arc looks like.

8 min

Semaglutide: What It Is, How It Works, and What It Costs

Semaglutide is the active ingredient in Ozempic and Wegovy. What it does, what the trials actually showed, what it costs in 2026, and where compounded versions now stand.

8 min

Tirzepatide: How It Works, What It Costs, and the Compounding Question

Tirzepatide is the active ingredient in Mounjaro and Zepbound, and it acts on two hormone receptors rather than one. What that changes, what the trials showed, and where compounded versions now stand.

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9 min

Tirzepatide vs. Semaglutide: How They Differ and Which Works Better

In the only head-to-head trial, tirzepatide produced 20.2% weight loss against semaglutide's 13.7% over 72 weeks. Here is what that means, and the cases where semaglutide is still the better choice.

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