iThriveMD
Verified listingAbout iThriveMD
iThriveMD's Laguna Niguel clinic sits at 24022 Aliso Creek Rd, Laguna Niguel, CA 92677. It is cash-pay: "No insurance or referral required." Consultations are free. Semaglutide injections start at $299 and tirzepatide at $399, and memberships start at $399, $599 and $799 a month. Every one of those figures is a network price rather than a Laguna Niguel price.
## What does the clinic offer?
Weight loss, hormones including TRT and female bioidentical hormone replacement, longevity, peptides, diagnostics, IV therapy, NAD+ injections, NAD+ wafers, glutathione injections and nutrient injections, plus telehealth. The medications named are semaglutide, tirzepatide, enclomiphene, HCG, sermorelin, NAD+, glutathione, GHK-Cu and methylene blue. Hours are 8:00 am to 6:00 pm Monday through Friday and 9:00 am to 5:00 pm on weekends.
## What does it cost?
Almost every figure is hedged with "starting at," "from" or "as low as," so read them as floors rather than quotes. Semaglutide injections start at $299.00 and tirzepatide injections at $399.00. A three-month microdosing tirzepatide program starts at $585.00, and GLP-1 plus GIP starts at $399.00. TRT with enclomiphene and female bioidentical hormone replacement each start at $289.00. Sermorelin and NAD+ injections start at $249.00, NAD+ wafers at $100.00, glutathione injections at $45.00, nutrient injections at $25.00 and custom IV therapy at $350.00.
Two of the lowest numbers carry a condition that has to travel with them. Microdosing tirzepatide at $146.25 a month and TRT at $199.20 a month both require a twelve-month program paid in full. A discount layer also exists, a 90-day membership unlock advertised at up to 75% off, with member prices shown against list prices in pairs: NAD+ at $249 and $79, sermorelin at $249 and $79, methylene blue at $99 and $29. Those are list and member figures, not ranges.
## How do the memberships bill?
The iThrive360 tiers start as low as $399 a month for Core, $599 for Metabolic and $799 for Executive. Here is the detail that is easy to miss: "All memberships will be charged every 28 days from the start of the membership." Every 28 days is thirteen charges a year, not twelve, so budget for that. No minimum commitment and no cancellation policy is published, and there is no terms page or membership agreement to read.
## Who would you see, and how far does care reach?
Twelve practitioners are listed under the location page, including Dr. Samir Damani, MD, and several naturopathic doctors. We could not determine whether that is the Laguna Niguel staff or the whole ten-clinic network's roster rendered on every city page, so we are not telling you which of them will be in the room. Credentials render inconsistently across the site, and we did not expand any of them. Telehealth scope is published twice and differently: California on the telehealth page, California and Arizona on the locations page. The site is set up to run Cherry, a third-party credit approval, before treatment, though the telehealth page adds "Not approved by Cherry? Your consult is still free." The Laguna Niguel phone carries a San Diego area code. All of this was checked on 22 September 2026.
**Sources:** https://www.ithrivemd.com/location/ca/laguna-niguel/ · https://www.ithrivemd.com/weight-loss/ · https://www.ithrivemd.com/hormones/ · https://www.ithrivemd.com/membership/ · https://www.ithrivemd.com/telehealth/ · https://www.ithrivemd.com/locations/